Survival Analysis, Overview
ثبت نشده
چکیده
Survival analysis is the study of the distribution of life times, that is, the times from an initiating event (birth, start of treatment, employment in a given job) to some terminal event (death, relapse, disability pension). A distinguishing feature of survival data is the inevitable presence of incomplete observations, particularly when the terminal event for some individuals is not observed; instead, it is only known that this event is at least later than a given point in time: right censoring (see Censored Data). The aims of this entry are to provide a brief historical sketch of the long development of survival analysis and to survey what we have found to be central issues in the current methodology of survival analysis. Necessarily, this entry is rich in crossreferences to other entries that treat specific subjects in more detail. However, we have not attempted to include cross-references to all specific entries within survival analysis.
منابع مشابه
An overview of semiparametric models in survival analysis
We provide an overview of semiparametric models commonly used in survival analysis, including proportional hazards model, proportional odds models and linear transformation models. The applications of these models to different types of censored data, either univariate or multivariate survival analysis, are given. For each case, inference procedures using censored observations are discussed. & 2...
متن کاملDopamine-Synthesizing Neurons: An Overview of Their Development and Application for Cell Therapy
Cell-gene therapy is a dynamic constituent of novel medical biotechnology. Neurodegenerative disordersin which damage to or demise of specific brain cell types plays central role, are clear examples of diseasecandidate for cell replacement therapy. Dopaminergic (DAergic) neurons biosynthesize dopamine, a vitalneurotransmitter in the central nervous system. Due to the involveme...
متن کاملPediatric kidney transplantation: An overview
Kidney Transplantation in children is the treatment of choice to treat end stage renal disease. Improvements in immunosuppressive management have dramatically reduced the risk of early acute rejection and graft loss, however the long term results in terms of graft survival and morbidity still require search for new immunosuppressive regimens. Reducing of side effects are the challenges for impr...
متن کاملApplied Medical Informatics
Survival analysis is one of the main areas of focus in medical research in recent years. Survival analysis involves the concept of 'Time to event'. The event may be mortality, onset of disease, response to treatment etc. Purpose of this paper is to provide overview of frequentist and Bayesian Approaches to Survival Analysis. The paper starts with the overview of the basic concepts of survival a...
متن کاملAn Overview of Fixed and Removable Orthodontic Retainers
Background and purpose: One of the main challenges in orthodontic treatment is relapse after treatment and return of the teeth to its original position. Therefore, retainers are an essential part of orthodontic treatment. Fixed and removable retainers are commonly used in orthodontic retention. They prevent relapse and require patientchr('39')s cooperation in using them. This review study aime...
متن کاملSurviving the Interim: Insights Into Interim Survival Analysis
Pre-specified interim analyses may be performed to evaluate whether a clinical trial can be halted prematurely for overwhelming efficacy and/or futility. This approach is somewhat more complex when the primary endpoint is a survival analysis. This paper provides an overview of performing the initial calculations and actual interim analyses using SAS ® PROC SEQDESIGN and PROC SEQTEST, EAST ® sof...
متن کامل